Factors influencing the requirements of thyroxin sodium treatment
Increased requirement
 | Pregnancy |
Drugs leading to decreased absorption of thyroxine
|
| Sucralfate |
|
| Aluminium hydroxide |
|
| Ferrous sulphate |
Drugs leading to increased clearance of thyroxine
|
| Rifampicin |
|
| Carbamazepine |
|
| Phenytoin |
Drugs that prevent conversion of T4 to T3
|
| Glucocorticoids |
|
| Amiodarone |
Depending on the above factors dose of thyroxin sodium may need adjustment.